The phrase "big inconvenience" means a significant problem or annoyance that causes trouble or inconvenience to someone.
Sentences with «big inconvenience»
Big inconvenience for my moms O2 medical device and food! (luxuryretreats.com)
But mostly I see that time of the month as a fairly big inconvenience and therefore want to take care of it in the most convenient way possible. (sortacrunchy.net)
However, an even bigger inconvenience would be having to fork out hundreds of thousands of dollars in medical bills. (adventureinyou.com)